New AI Technology Revolutionizes Male Infertility Treatment

Artificial intelligence (AI) presents a breakthrough in the field of male infertility treatment. Dr. Steven Vasilescu and his team at the University of Technology Sydney have developed an AI software called SpermSearch, which can detect viable sperm in samples from severely infertile men 1,000 times faster than a highly trained professional. This innovative technology offers hope for men who have no sperm in their ejaculate, a condition known as non-obstructive azoospermia (NOA).

Traditionally, embryologists manually search for healthy sperm by examining surgically removed testes tissue under a microscope, a process that is time-consuming and prone to fatigue and inaccuracy. Dr. Vasilescu explains that the tissue samples often contain various cells, making it difficult to find the few viable sperm present. However, SpermSearch can identify healthy sperm within seconds by analyzing photographs of the samples uploaded into the computer. The AI software has been trained using thousands of images, enabling it to quickly and accurately identify sperm in complex tissue samples.

Speed is crucial in this process, as there is a small time window to fertilize eggs after an egg collection. With SpermSearch’s ability to rapidly locate viable sperm, the chances of successful fertilization are significantly increased. This technology aims to assist embryologists rather than replace them, providing them with an efficient and precise tool to enhance their workflow.

As male fertility rates have been declining over the past four decades, advancements in infertility treatment are crucial. Various factors, including pollution, smoking, poor diets, lack of exercise, and high stress levels, contribute to this decline. Dr. Meurig Gallagher from the University of Birmingham has also developed a new technique using imaging software to track the speed and movement of sperm tails, providing insight into their health and response to environmental factors.

While AI in infertility treatment shows promise, it is still in the early stages of development. SpermSearch is currently in the proof-of-concept phase after a small trial involving seven patients. The transition from proof-of-concept to commercial availability can take between two and five years. However, Dr. Vasilescu remains optimistic and aims to conduct clinical trials in the near future, with the ultimate goal of achieving live pregnancies through the use of AI technology.


1. What is non-obstructive azoospermia (NOA)?

Non-obstructive azoospermia is a condition characterized by the absence of sperm in the ejaculate due to a problem in sperm production within the testes.

2. Can AI technology replace human embryologists?

No, AI technology is designed to assist human embryologists rather than replace them. It provides a faster and more accurate method of identifying viable sperm in complex tissue samples, improving the efficiency and success rates of infertility treatments.

3. How long does it take to transition AI technology from proof-of-concept to commercial availability?

The transition from the proof-of-concept phase to commercial availability typically takes between two and five years in the field of medicine. However, further research and clinical trials are required to ensure the safety and effectiveness of the AI technology in treating male infertility.